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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2031
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ada
Name: adenosine deaminase
Acc ID: CHEBI:35456
Term: cadmium dichloride
Definition: A cadmium coordination entity in which cadmium(2+) and Cl(-) ions are present in the ratio 2:1. Although considered to be ionic, it has considerable covalent character to its bonding.
Chemical ID: MESH:D019256
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Adaincreases activityEXP 6480464CTDCadmium Chloride results in increased activity of ADA proteinPMID:25064450
Adaincreases methylationEXP 6480464CTDCadmium Chloride results in increased methylation of ADA promoterPMID:22457795
Adamultiple interactionsEXP 6480464CTDQuercetin inhibits the reaction [Cadmium Chloride results in increased activity of ADA protein]PMID:25064450
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