Gene Chemical Interaction Report - Rat Genome Database

Submit Data | Help | Video Tutorials | News | Publications | Download | REST API | Citing RGD | Contact

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	1552455
Species:	Mus musculus
RGD Object:	Gene
Symbol:	Fas
Name:	Fas cell surface death receptor

Acc ID:	CHEBI:35456
Term:	cadmium dichloride
Definition:	A cadmium coordination entity in which cadmium(2+) and Cl(-) ions are present in the ratio 2:1. Although considered to be ionic, it has considerable covalent character to its bonding.
Chemical ID:	MESH:D019256

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
Fas	increases expression	EXP		6480464	CTD	Cadmium Chloride results in increased expression of FAS protein	PMID:16421179 PMID:21420465
Fas	multiple interactions	EXP		6480464	CTD	[Mercuric Chloride co-treated with sodium arsenite co-treated with Cadmium Chloride] results in increased expression of FAS protein; arjunolic acid inhibits the reaction [Cadmium Chloride results in increased expression of FAS protein]	PMID:16421179 PMID:21420465
Fas	decreases expression	ISO	FAS (Homo sapiens)	6480464	CTD	Cadmium Chloride results in decreased expression of FAS mRNA	PMID:12160620
Fas	increases expression	ISO	FAS (Homo sapiens)	6480464	CTD	Cadmium Chloride results in increased expression of FAS mRNA; Cadmium Chloride results in increased expression of FAS protein	PMID:23485651 PMID:25596134
Fas	increases expression	ISO	Fas (Rattus norvegicus)	6480464	CTD	Cadmium Chloride results in increased expression of FAS mRNA	PMID:25993096

Go Back to source page

Continue to Ontology report