Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1347174
Species: Homo sapiens
RGD Object: Gene
Symbol: ACE2
Name: angiotensin converting enzyme 2
Acc ID: CHEBI:35456
Term: cadmium dichloride
Definition: A cadmium coordination entity in which cadmium(2+) and Cl(-) ions are present in the ratio 2:1. Although considered to be ionic, it has considerable covalent character to its bonding.
Chemical ID: MESH:D019256
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ACE2decreases expressionISOAce2 (Mus musculus)6480464CTDCadmium Chloride results in decreased expression of ACE2 proteinPMID:35844137
ACE2increases methylationISOAce2 (Rattus norvegicus)6480464CTDCadmium Chloride results in increased methylation of ACE2 promoterPMID:22457795
ACE2multiple interactionsISOAce2 (Mus musculus)6480464CTDMelatonin inhibits the reaction [Cadmium Chloride results in decreased expression of ACE2 protein]PMID:35844137
Go Back to source page   Continue to Ontology report