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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11035
Species: Mus musculus
RGD Object: Gene
Symbol: Tnfrsf11b
Name: tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)
Acc ID: CHEBI:35456
Term: cadmium dichloride
Definition: A cadmium coordination entity in which cadmium(2+) and Cl(-) ions are present in the ratio 2:1. Although considered to be ionic, it has considerable covalent character to its bonding.
Chemical ID: MESH:D019256
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tnfrsf11bmultiple interactionsEXP 6480464CTD[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of TNFRSF11B proteinPMID:31793751
Tnfrsf11bdecreases expressionISOTnfrsf11b (Rattus norvegicus)6480464CTDCadmium Chloride results in decreased expression of TNFRSF11B proteinPMID:23726800 PMID:25656917
Tnfrsf11bmultiple interactionsISOTnfrsf11b (Rattus norvegicus)6480464CTDPlant Extracts inhibits the reaction [Cadmium Chloride results in decreased expression of TNFRSF11B protein]; Polyphenols inhibits the reaction [Cadmium Chloride results in decreased expression of TNFRSF11B protein]; zinc chloride inhibits the reaction [Cadmium Chloride results in decreased expression of TNFRSF11B protein]PMID:23726800 PMID:25656917
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