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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10857
Species: Mus musculus
RGD Object: Gene
Symbol: Lamp2
Name: lysosomal-associated membrane protein 2
Acc ID: CHEBI:35456
Term: cadmium dichloride
Definition: A cadmium coordination entity in which cadmium(2+) and Cl(-) ions are present in the ratio 2:1. Although considered to be ionic, it has considerable covalent character to its bonding.
Chemical ID: MESH:D019256
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lamp2increases expressionEXP 6480464CTDCadmium Chloride results in increased expression of LAMP2 mRNAPMID:30030080
Lamp2multiple interactionsEXP 6480464CTD[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of LAMP2 proteinPMID:31862506
Lamp2multiple interactionsISOLamp2 (Rattus norvegicus)6480464CTD[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of LAMP2 protein; brusatol inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of LAMP2 protein]; NFE2L2 protein inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of LAMP2 protein]PMID:34695510
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