GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | SLC10A1 | decreases expression | ISO | Slc10a1 (Rattus norvegicus) | 15090803 | RGD | 1-naphthyl isothiocyanate decreases expression of Slc10a1 protein in rat liver | | SLC10A1 | decreases expression | ISO | Slc10a1 (Mus musculus) | 6480464 | CTD | 1-Naphthylisothiocyanate results in decreased expression of SLC10A1 mRNA; 1-Naphthylisothiocyanate results in decreased expression of SLC10A1 protein | PMID:19181614 PMID:25655198 PMID:29660435 PMID:30517764 PMID:32579994 PMID:32976922 PMID:33749747 PMID:36008890 | SLC10A1 | decreases expression | ISO | Slc10a1 (Rattus norvegicus) | 6480464 | CTD | 1-Naphthylisothiocyanate results in decreased expression of SLC10A1 mRNA; 1-Naphthylisothiocyanate results in decreased expression of SLC10A1 protein | PMID:14623915 PMID:24120425 PMID:25418378 PMID:26365562 PMID:27317372 PMID:27702592 PMID:27765674 PMID:30723492 PMID:32198087 | SLC10A1 | multiple interactions | ISO | Slc10a1 (Mus musculus) | 6480464 | CTD | [1-Naphthylisothiocyanate co-treated with obeticholic acid] results in decreased expression of SLC10A1 protein; [1-Naphthylisothiocyanate co-treated with ursodoxicoltaurine] results in decreased expression of SLC10A1 protein; [NR1H4 protein results in increased susceptibility to 1-Naphthylisothiocyanate] which results in decreased expression of SLC10A1 mRNA; alisol B 23-acetate promotes the reaction [1-Naphthylisothiocyanate results in decreased expression of SLC10A1 mRNA]; Allopurinol inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of SLC10A1 mRNA]; Chenodeoxycholic Acid inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of SLC10A1 mRNA]; Emodin inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of SLC10A1 mRNA]; liquiritin inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of SLC10A1 mRNA]; NFE2L2 inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of SLC10A1 mRNA]; NR1H4 promotes the reaction [1-Naphthylisothiocyanate results in decreased expression of SLC10A1 mRNA]; NR1H4 promotes the reaction [yangonin promotes the reaction [1-Naphthylisothiocyanate results in decreased expression of SLC10A1 mRNA]]; obeticholic acid promotes the reaction [1-Naphthylisothiocyanate results in decreased expression of SLC10A1 mRNA]; obeticholic acid promotes the reaction [1-Naphthylisothiocyanate results in decreased expression of SLC10A1 protein]; picroside II inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of SLC10A1 mRNA]; pregna-4,17-diene-3,16-dione inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of SLC10A1 mRNA]; pregna-4,17-diene-3,16-dione inhibits the reaction [alisol B 23-acetate promotes the reaction [1-Naphthylisothiocyanate results in decreased expression of SLC10A1 mRNA]]; pregna-4,17-diene-3,16-dione inhibits the reaction [yangonin promotes the reaction [1-Naphthylisothiocyanate results in decreased expression of SLC10A1 mRNA]]; SEW2871 inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of SLC10A1 mRNA]; SEW2871 inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of SLC10A1 protein]; Uric Acid inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of SLC10A1 mRNA]; yangonin promotes the reaction [1-Naphthylisothiocyanate results in decreased expression of SLC10A1 mRNA]; yangonin promotes the reaction [1-Naphthylisothiocyanate results in decreased expression of SLC10A1 protein] | PMID:19181614 PMID:25655198 PMID:29660435 PMID:29968724 PMID:30517764 PMID:32579994 PMID:32976922 PMID:33749747 PMID:36008890 PMID:36787806 | SLC10A1 | multiple interactions | ISO | Slc10a1 (Rattus norvegicus) | 6480464 | CTD | dioscin inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of SLC10A1 mRNA]; ginsenoside Rg1 inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of SLC10A1 mRNA]; ginsenoside Rg1 inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of SLC10A1 protein]; Ursodeoxycholic Acid inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of SLC10A1 mRNA]; Ursodeoxycholic Acid inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of SLC10A1 protein] | PMID:27317372 PMID:32198087 | | ||||||||||||||||||||||
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