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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732220
Species: Mus musculus
RGD Object: Gene
Symbol: Abcg5
Name: ATP binding cassette subfamily G member 5
Acc ID: CHEBI:35455
Term: 1-naphthyl isothiocyanate
Definition: An isothiocyanate that has formula C11H7NS.
Chemical ID: MESH:D015058
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcg5decreases expressionEXP 6480464CTD1-Naphthylisothiocyanate results in decreased expression of ABCG5 mRNAPMID:28549656
Abcg5multiple interactionsEXP 6480464CTD18alpha-glycyrrhetinic acid inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of ABCG5 mRNA]PMID:28549656
Abcg5decreases expressionISOAbcg5 (Rattus norvegicus)6480464CTD1-Naphthylisothiocyanate results in decreased expression of ABCG5 mRNAPMID:25380136 PMID:27765674 PMID:30723492
Abcg5increases expressionISOAbcg5 (Rattus norvegicus)6480464CTD1-Naphthylisothiocyanate results in increased expression of ABCG5 mRNAPMID:27765674
Abcg5multiple interactionsISOABCG5 (Homo sapiens)6480464CTD[1-Naphthylisothiocyanate co-treated with Cholic Acids] affects the expression of ABCG5 mRNAPMID:27344345
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