GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Abcc3 | increases expression | EXP | | 6480464 | CTD | 1-Naphthylisothiocyanate results in increased expression of ABCC3 mRNA; 1-Naphthylisothiocyanate results in increased expression of ABCC3 protein | PMID:14623915 PMID:17522070 PMID:25418378 PMID:26365562 PMID:27765674 PMID:30723492 | Abcc3 | multiple interactions | EXP | | 6480464 | CTD | resveratrol inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of ABCC3 mRNA]; resveratrol inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of ABCC3 protein]; Ursodeoxycholic Acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of ABCC3 protein] | PMID:25418378 | Abcc3 | affects expression | ISO | Abcc3 (Mus musculus) | 6480464 | CTD | 1-Naphthylisothiocyanate affects the expression of ABCC3 mRNA | PMID:28549656 | Abcc3 | decreases expression | ISO | Abcc3 (Mus musculus) | 6480464 | CTD | 1-Naphthylisothiocyanate results in decreased expression of ABCC3 mRNA | PMID:30517764 | Abcc3 | increases expression | ISO | Abcc3 (Mus musculus) | 6480464 | CTD | 1-Naphthylisothiocyanate results in increased expression of ABCC3 mRNA; 1-Naphthylisothiocyanate results in increased expression of ABCC3 protein | PMID:19181614 PMID:19407337 PMID:25655198 PMID:32579994 PMID:33749747 | Abcc3 | multiple interactions | ISO | Abcc3 (Mus musculus) | 6480464 | CTD | 18alpha-glycyrrhetinic acid affects the reaction [1-Naphthylisothiocyanate affects the expression of ABCC3 mRNA]; [1-Naphthylisothiocyanate co-treated with Uric Acid] results in increased expression of ABCC3 mRNA; [liquiritin co-treated with 1-Naphthylisothiocyanate] results in increased expression of ABCC3 mRNA; [obeticholic acid co-treated with 1-Naphthylisothiocyanate] results in increased expression of ABCC3 protein; [PPARA protein affects the susceptibility to 1-Naphthylisothiocyanate] which affects the expression of ABCC3 mRNA; Glycyrrhizic Acid affects the reaction [1-Naphthylisothiocyanate affects the expression of ABCC3 mRNA]; NFE2L2 promotes the reaction [1-Naphthylisothiocyanate results in increased expression of ABCC3 mRNA]; SEW2871 inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of ABCC3 protein]; Uric Acid promotes the reaction [1-Naphthylisothiocyanate results in increased expression of ABCC3 mRNA] | PMID:19181614 PMID:28549656 PMID:30352267 PMID:32579994 PMID:33749747 PMID:36008890 PMID:36787806 | | ||||||||||||||||||||||
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