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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1352146
Species: Homo sapiens
RGD Object: Gene
Symbol: MT2A
Name: metallothionein 2A
Acc ID: CHEBI:35455
Term: 1-naphthyl isothiocyanate
Definition: An isothiocyanate that has formula C11H7NS.
Chemical ID: MESH:D015058
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MT2Adecreases expressionISOMt2A (Rattus norvegicus)6480464CTD1-Naphthylisothiocyanate results in decreased expression of MT2A mRNAPMID:30723492
MT2Aincreases expressionISOMt2A (Rattus norvegicus)6480464CTD1-Naphthylisothiocyanate results in increased expression of MT2A mRNAPMID:25380136
MT2Aincreases expressionISOMt2 (Mus musculus)6480464CTD1-Naphthylisothiocyanate results in increased expression of MT2 mRNAPMID:27853831
MT2Amultiple interactionsISOMt2 (Mus musculus)6480464CTDpirinixic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of MT2 mRNA]; PPARA protein affects the reaction [pirinixic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of MT2 mRNA]]PMID:27853831
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