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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730996
Species: Mus musculus
RGD Object: Gene
Symbol: Hsf1
Name: heat shock factor 1
Acc ID: CHEBI:35176
Term: zinc sulfate
Definition: A metal sulfate compound having zinc(2+) as the counterion.
Chemical ID: MESH:D019287
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hsf1increases activityISOHSF1 (Homo sapiens)6480464CTDZinc Sulfate results in increased activity of HSF1 proteinPMID:16460681 PMID:17244614
Hsf1multiple interactionsISOHSF1 (Homo sapiens)6480464CTDZinc Sulfate promotes the reaction [HSF1 protein binds to HMOX1 promoter]; Zinc Sulfate promotes the reaction [HSF1 protein binds to HSPA1A enhancer]; Zinc Sulfate promotes the reaction [HSF1 protein binds to HSPA1A promoter]; Zinc Sulfate promotes the reaction [MTF1 protein binds to HSF1 protein]PMID:16460681 PMID:17244614
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