GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Slc12a2 | increases expression | ISO | Slc12a2 (Rattus norvegicus) | 6480464 | CTD | Manganese results in increased expression of SLC12A2 protein | PMID:25817889 | Slc12a2 | increases oxidation | ISO | Slc12a2 (Rattus norvegicus) | 6480464 | CTD | Manganese results in increased oxidation of SLC12A2 protein | PMID:25817889 | Slc12a2 | multiple interactions | ISO | Slc12a2 (Rattus norvegicus) | 6480464 | CTD | 1,3-dimethylthiourea inhibits the reaction [Manganese results in increased expression of SLC12A2 protein]; 1,3-dimethylthiourea inhibits the reaction [Manganese results in increased oxidation of SLC12A2 protein]; Bumetanide inhibits the reaction [Manganese results in increased expression of SLC12A2 protein]; Bumetanide inhibits the reaction [Manganese results in increased oxidation of SLC12A2 protein]; Bumetanide inhibits the reaction [Manganese results in increased phosphorylation of and results in increased activity of SLC12A2 protein]; CAT protein inhibits the reaction [Manganese results in increased expression of SLC12A2 protein]; CAT protein inhibits the reaction [Manganese results in increased phosphorylation of and results in increased activity of SLC12A2 protein]; Manganese results in increased phosphorylation of and results in increased activity of SLC12A2 protein; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Manganese results in increased expression of SLC12A2 protein]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Manganese results in increased oxidation of SLC12A2 protein]; tempol inhibits the reaction [Manganese results in increased expression of SLC12A2 protein]; tempol inhibits the reaction [Manganese results in increased oxidation of SLC12A2 protein]; Uric Acid inhibits the reaction [Manganese results in increased expression of SLC12A2 protein]; Uric Acid inhibits the reaction [Manganese results in increased phosphorylation of and results in increased activity of SLC12A2 protein]; Vitamin E inhibits the reaction [Manganese results in increased expression of SLC12A2 protein]; Vitamin E inhibits the reaction [Manganese results in increased phosphorylation of and results in increased activity of SLC12A2 protein] | PMID:25817889 | |
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