GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | PTGS2 | increases expression | EXP | | 6480464 | CTD | Manganese results in increased expression of PTGS2 mRNA; Manganese results in increased expression of PTGS2 protein | PMID:17175027 | PTGS2 | multiple interactions | ISO | Ptgs2 (Rattus norvegicus) | 6480464 | CTD | [Curcumin co-treated with Manganese] inhibits the reaction [Kainic Acid results in increased expression of PTGS2 mRNA]; [diacetylcurcumin co-treated with Manganese] inhibits the reaction [Kainic Acid results in increased expression of PTGS2 mRNA]; [manganese chloride results in increased abundance of Manganese] promotes the reaction [Ethanol results in increased expression of PTGS2 protein]; [manganese chloride results in increased abundance of Manganese] which results in increased expression of PTGS2 protein; Ethanol promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of PTGS2 protein] | PMID:17827730 PMID:30844427 PMID:33314588 | PTGS2 | multiple interactions | ISO | Ptgs2 (Mus musculus) | 6480464 | CTD | [Manganese co-treated with Lipopolysaccharides] results in increased expression of PTGS2 mRNA | PMID:20589745 | | ||||||||||||||||||||||
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