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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1308236
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc39a8
Name: solute carrier family 39 member 8
Acc ID: CHEBI:35154
Term: manganese(0)
Definition: An elemental manganese that has formula Mn.
Chemical ID: MESH:D008345
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc39a8increases importEXP 6480464CTDSLC39A8 protein results in increased import of ManganesePMID:22898811
Slc39a8multiple interactionsEXP 6480464CTDManganese inhibits the reaction [SLC39A8 protein results in increased import of Iron]PMID:22898811
Slc39a8affects transportISOSLC39A8 (Homo sapiens)6480464CTDSLC39A8 gene SNP affects the transport of Manganese; SLC39A8 SNP affects the transport of ManganesePMID:26025379 PMID:28917719
Slc39a8increases uptakeISOSlc39a8 (Mus musculus)6480464CTDSLC39A8 protein results in increased uptake of ManganesePMID:16638970
Slc39a8multiple interactionsISOSlc39a8 (Mus musculus)6480464CTDManganese inhibits the reaction [SLC39A8 protein results in increased uptake of Cadmium]; SLC39A8 protein results in increased uptake of [Manganese co-treated with Bicarbonates]PMID:16638970
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