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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2426
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Csf3
Name: colony stimulating factor 3
Acc ID: CHEBI:351346
Term: phenethyl isothiocyanate
Definition: An isothiocyanate having a phenethyl group attached to the nitrogen. It is a naturally occurring compound found in some cruciferous vegetables (e.g. watercress) and is known to possess anticancer properties.
Chemical ID: MESH:C058305
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:7314166480464CTDphenethyl isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased expression of CSF3 mRNA]

PMID:20423518
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.