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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 734253
Species: Mus musculus
RGD Object: Gene
Symbol: Kmo
Name: kynurenine 3-monooxygenase
Acc ID: CHEBI:34953
Term: Ro 61-8048
Definition: A C-nitro compound that has formula C17H15N3O6S2.
Chemical ID: MESH:C110196
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Kmodecreases activityISOKmo (Rattus norvegicus)6480464CTDRo 61-8048 results in decreased activity of KMO proteinPMID:30151725
Kmomultiple interactionsISOKmo (Rattus norvegicus)6480464CTD[Ro 61-8048 results in decreased activity of KMO protein] which results in increased abundance of Kynurenic AcidPMID:30151725
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