GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | NR4A2 | affects binding | EXP | | 6480464 | CTD | Permethrin binds to [NR4A2 protein binds to NR4A2 protein] | PMID:31175960 | NR4A2 | affects expression | ISO | Nr4a2 (Rattus norvegicus) | 6480464 | CTD | Permethrin affects the expression of NR4A2 mRNA | PMID:23566817 | NR4A2 | decreases expression | ISO | Nr4a2 (Rattus norvegicus) | 6480464 | CTD | Permethrin results in decreased expression of NR4A2; Permethrin results in decreased expression of NR4A2 mRNA; Permethrin results in decreased expression of NR4A2 protein | PMID:22056222 PMID:23174539 PMID:25048945 | NR4A2 | increases expression | ISO | Nr4a2 (Rattus norvegicus) | 6480464 | CTD | Permethrin results in increased expression of NR4A2 mRNA; Permethrin results in increased expression of NR4A2 protein | PMID:23566817 PMID:28943456 PMID:29051472 PMID:31175960 | NR4A2 | multiple interactions | ISO | Nr4a2 (Rattus norvegicus) | 6480464 | CTD | Glutathione inhibits the reaction [Permethrin results in increased expression of NR4A2 mRNA]; Tocotrienols inhibits the reaction [Permethrin results in increased expression of NR4A2 mRNA] | PMID:28943456 | |
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