GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mapk1 | increases phosphorylation | EXP | | 6480464 | CTD | Permethrin results in increased phosphorylation of MAPK1 protein | PMID:31621018 | Mapk1 | multiple interactions | EXP | | 6480464 | CTD | [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of MAPK1 mRNA; Matrines inhibits the reaction [Permethrin results in increased phosphorylation of MAPK1 protein] | PMID:28659758 PMID:31621018 | Mapk1 | decreases methylation | ISO | MAPK1 (Homo sapiens) | 6480464 | CTD | Permethrin results in decreased methylation of MAPK1 promoter | PMID:37047231 | Mapk1 | increases phosphorylation | ISO | MAPK1 (Homo sapiens) | 6480464 | CTD | Permethrin results in increased phosphorylation of MAPK1 protein | PMID:30205134 | Mapk1 | multiple interactions | ISO | MAPK1 (Homo sapiens) | 6480464 | CTD | 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Permethrin results in increased phosphorylation of MAPK1 protein]; 3,5-dihydroxyphenylglycine promotes the reaction [Permethrin results in increased phosphorylation of MAPK1 protein]; [Permethrin co-treated with INS protein] results in increased phosphorylation of MAPK1 protein; bisindolylmaleimide I inhibits the reaction [Permethrin results in increased phosphorylation of MAPK1 protein]; N-phenyl-7-(hydroxyimino)cyclopropa(b)chromen-1a-carboxamide inhibits the reaction [Permethrin results in increased phosphorylation of MAPK1 protein]; Tetrodotoxin inhibits the reaction [Permethrin results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [[Permethrin co-treated with INS protein] results in increased phosphorylation of MAPK1 protein] | PMID:28866332 PMID:30205134 | | ||||||||||||||||||||||
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