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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2890
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il1a
Name: interleukin 1 alpha
Acc ID: CHEBI:34911
Term: permethrin
Definition: A cyclopropanecarboxylate ester in which the esterifying alcohol is 3-phenoxybenzyl alcohol and the cyclopropane ring is substituted with a 2,2-dichlorovinyl group and with gem-dimethyl groups.
Chemical ID: MESH:D026023
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il1amultiple interactionsEXP 6480464CTD[Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of and results in increased secretion of IL1A protein; [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of IL1A mRNAPMID:28659758
Il1adecreases expressionISOIL1A (Homo sapiens)6480464CTDPermethrin results in decreased expression of IL1A mRNAPMID:37047231
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