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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731948
Species: Mus musculus
RGD Object: Gene
Symbol: Slc6a2
Name: solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
Acc ID: CHEBI:34910
Term: pentetrazol
Definition: An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.
Chemical ID: MESH:D010433
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc6a2increases response to substanceEXP 6480464CTDSLC6A2 protein results in increased susceptibility to PentylenetetrazolePMID:15911120
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