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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1323522
Species: Homo sapiens
RGD Object: Gene
Symbol: NRIP1
Name: nuclear receptor interacting protein 1
Acc ID: CHEBI:34907
Term: paxilline
Definition: An indole diterpene alkaloid with formula C27H33NO4 isolated from Penicillium paxilli. It is a potent inhibitor of large conductance Ca2(+)- and voltage-activated K(+) (BK)-type channels.
Chemical ID: MESH:C048220
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NRIP1increases expressionEXP 6480464CTDpaxilline results in increased expression of NRIP1 mRNAPMID:32123961
NRIP1multiple interactionsEXP 6480464CTD[CD 3254 co-treated with paxilline] results in increased expression of NRIP1 mRNAPMID:32123961
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