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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737440
Species: Mus musculus
RGD Object: Gene
Symbol: Serpinh1
Name: serine (or cysteine) peptidase inhibitor, clade H, member 1
Acc ID: CHEBI:34905
Term: paraquat
Definition: An organic cation that consists of 4,4'-bipyridine bearing two N-methyl substituents loctated at the 1- and 1'-positions.
Chemical ID: MESH:D010269
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Serpinh1decreases expressionEXP 6480464CTDParaquat results in decreased expression of SERPINH1 mRNAPMID:21463325
Serpinh1increases response to substanceISOSerpinh1 (Rattus norvegicus)6480464CTDSERPINH1 protein results in increased susceptibility to ParaquatPMID:17543438
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