GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | APP | increases expression | EXP | | 6480464 | CTD | Paraquat results in increased expression of APP mRNA; Paraquat results in increased expression of APP protein | PMID:27793699 | APP | increases response to substance | EXP | | 6480464 | CTD | APP protein results in increased susceptibility to Paraquat | PMID:23827522 | APP | multiple interactions | EXP | | 6480464 | CTD | Carnitine promotes the reaction [Paraquat deficiency inhibits the reaction [Paraquat promotes the reaction [APP protein binds to APP protein]]]; Curcumin inhibits the reaction [Paraquat results in increased expression of APP mRNA]; Curcumin inhibits the reaction [Paraquat results in increased expression of APP protein]; Paraquat deficiency inhibits the reaction [Paraquat promotes the reaction [APP protein binds to APP protein]]; Paraquat promotes the reaction [APP protein binds to APP protein] | PMID:27793699 PMID:33290254 | APP | increases expression | ISO | App (Rattus norvegicus) | 6480464 | CTD | Paraquat results in increased expression of APP protein; Paraquat results in increased expression of APP protein alternative form | PMID:31715309 PMID:32738378 | APP | multiple interactions | ISO | App (Rattus norvegicus) | 6480464 | CTD | [BDNF protein co-treated with MF63 compound co-treated with Estradiol] inhibits the reaction [Paraquat results in increased expression of APP protein alternative form]; [BDNF protein co-treated with MF63 compound] promotes the reaction [Estradiol inhibits the reaction [Paraquat results in increased expression of APP protein alternative form]]; BDNF protein inhibits the reaction [Paraquat results in increased expression of APP protein alternative form]; Estradiol inhibits the reaction [Paraquat results in increased expression of APP protein alternative form]; Estradiol inhibits the reaction [Paraquat results in increased expression of APP protein]; MF63 compound inhibits the reaction [Paraquat results in increased expression of APP protein alternative form] | PMID:31715309 PMID:32738378 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |