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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 734300
Species: Mus musculus
RGD Object: Gene
Symbol: Bcl2l11
Name: BCL2 like 11
Acc ID: CHEBI:34905
Term: paraquat
Definition: An organic cation that consists of 4,4'-bipyridine bearing two N-methyl substituents loctated at the 1- and 1'-positions.
Chemical ID: MESH:D010269
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bcl2l11increases expressionEXP 6480464CTDParaquat results in increased expression of BCL2L11 mRNAPMID:23620592
Bcl2l11multiple interactionsEXP 6480464CTDFOXO3 mutant form inhibits the reaction [Paraquat results in increased expression of BCL2L11 mRNA]PMID:23620592
Bcl2l11decreases expressionISOBCL2L11 (Homo sapiens)6480464CTDParaquat results in decreased expression of BCL2L11 mRNAPMID:18836921
Bcl2l11increases expressionISOBCL2L11 (Homo sapiens)6480464CTDParaquat results in increased expression of BCL2L11 proteinPMID:18266926
Bcl2l11multiple interactionsISOBCL2L11 (Homo sapiens)6480464CTD[Paraquat co-treated with Maneb] results in increased expression of BCL2L11 proteinPMID:18266926
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