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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1557476
Species: Mus musculus
RGD Object: Gene
Symbol: Plcb2
Name: phospholipase C, beta 2
Acc ID: CHEBI:34905
Term: paraquat
Definition: An organic cation that consists of 4,4'-bipyridine bearing two N-methyl substituents loctated at the 1- and 1'-positions.
Chemical ID: MESH:D010269
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Plcb2increases phosphorylationISOPLCB2 (Homo sapiens)6480464CTDParaquat results in increased phosphorylation of PLCB2 proteinPMID:20164675
Plcb2multiple interactionsISOPLCB2 (Homo sapiens)6480464CTDDapsone inhibits the reaction [Paraquat results in increased phosphorylation of PLCB2 protein]PMID:20164675
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