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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10796
Species: Mus musculus
RGD Object: Gene
Symbol: Il4
Name: interleukin 4
Acc ID: CHEBI:34905
Term: paraquat
Definition: An organic cation that consists of 4,4'-bipyridine bearing two N-methyl substituents loctated at the 1- and 1'-positions.
Chemical ID: MESH:D010269
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il4increases expressionEXP 6480464CTDParaquat results in increased expression of IL4 proteinPMID:28090784
Il4multiple interactionsEXP 6480464CTD[Resveratrol co-treated with Tetracyclines] inhibits the reaction [Paraquat results in increased expression of IL4 protein]PMID:28090784
Il4decreases expressionISOIl4 (Rattus norvegicus)6480464CTDParaquat results in decreased expression of IL4 mRNAPMID:24521700
Il4decreases expressionISOIL4 (Homo sapiens)6480464CTDParaquat results in decreased expression of IL4 proteinPMID:36108500
Il4increases expressionISOIl4 (Rattus norvegicus)6480464CTDParaquat results in increased expression of IL4 mRNAPMID:28467894
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