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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1557006
Species: Mus musculus
RGD Object: Gene
Symbol: Ccar1
Name: cell division cycle and apoptosis regulator 1
Acc ID: CHEBI:34892
Term: nocodazole
Definition: A member of the class of benzimidazoles that is benzimidalole which is substituted at position 2 by a (methoxycarbonyl)amino group and at position 5 by a 2-thienoyl group. It is an antineoplastic agent that exerts its effect by depolymerising microtubules.
Chemical ID: MESH:D015739
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ccar1increases expressionISOCCAR1 (Homo sapiens)6480464CTDNocodazole results in increased expression of CCAR1 proteinPMID:21903591
Ccar1multiple interactionsISOCCAR1 (Homo sapiens)6480464CTDNocodazole inhibits the reaction [sodium arsenite affects the localization of CCAR1 protein]; Nocodazole promotes the reaction [CCAR1 protein binds to ANAPC2 protein]PMID:19073175 PMID:21903591
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