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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735868
Species: Homo sapiens
RGD Object: Gene
Symbol: NQO1
Name: NAD(P)H quinone dehydrogenase 1
Acc ID: CHEBI:34887
Term: nickel dichloride
Definition: A compound of nickel and chloride in which the ratio of nickel (in the +2 oxidation state) to chloride is 1:2.
Chemical ID: MESH:C022838
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTDnickel chloride inhibits the reaction [Benzo(a)pyrene results in increased expression of NQO1 mRNA]

PMID:14645679
decreases expressionISORGD:104736480464CTDnickel chloride results in decreased expression of NQO1 mRNA

PMID:14645679
multiple interactionsISORGD:104736480464CTDnickel chloride inhibits the reaction [Benzo(a)pyrene results in increased expression of NQO1 mRNA]

PMID:14645679
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.