GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | ICAM1 | increases expression | EXP | | 6480464 | CTD | nickel chloride results in increased expression of ICAM1 mRNA; nickel chloride results in increased expression of ICAM1 protein | PMID:15737199 PMID:17312168 PMID:24080332 PMID:33774146 | ICAM1 | multiple interactions | EXP | | 6480464 | CTD | 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [nickel chloride results in increased expression of ICAM1 protein]; [nickel chloride results in increased phosphorylation of NFKBIA protein] inhibits the reaction [nickel chloride results in increased expression of ICAM1 protein]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [nickel chloride results in increased expression of ICAM1 protein]; MYD88 mutant form inhibits the reaction [nickel chloride results in increased expression of ICAM1 protein] | PMID:24080332 | ICAM1 | increases secretion | ISO | Icam1 (Mus musculus) | 6480464 | CTD | nickel chloride results in increased secretion of ICAM1 protein | PMID:19844976 | | ||||||||||||||||||||||
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