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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69062
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cdkn1b
Name: cyclin-dependent kinase inhibitor 1B
Acc ID: CHEBI:34887
Term: nickel dichloride
Definition: A compound of nickel and chloride in which the ratio of nickel (in the +2 oxidation state) to chloride is 1:2.
Chemical ID: MESH:C022838
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cdkn1baffects expressionEXP 6480464CTDnickel chloride affects the expression of CDKN1B mRNAPMID:22546817
Cdkn1bincreases expressionISOCDKN1B (Homo sapiens)6480464CTDnickel chloride results in increased expression of CDKN1B proteinPMID:28552779
Cdkn1bmultiple interactionsISOCDKN1B (Homo sapiens)6480464CTDHIF1A protein promotes the reaction [nickel chloride results in increased expression of CDKN1B protein]PMID:28552779
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