GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Hmox1 | affects expression | EXP | | 6480464 | CTD | nickel chloride affects the expression of HMOX1 mRNA | PMID:22546817 | Hmox1 | increases expression | EXP | | 6480464 | CTD | nickel chloride results in increased expression of HMOX1 mRNA | PMID:22110744 | Hmox1 | increases expression | ISO | HMOX1 (Homo sapiens) | 6480464 | CTD | nickel chloride results in increased expression of HMOX1 mRNA | PMID:17312168 PMID:17547211 PMID:18830972 PMID:21111804 | Hmox1 | multiple interactions | ISO | HMOX1 (Homo sapiens) | 6480464 | CTD | Acetylcysteine inhibits the reaction [nickel chloride promotes the reaction [lipopolysaccharide A results in increased expression of HMOX1 protein]]; Acetylcysteine inhibits the reaction [nickel chloride results in increased expression of HMOX1 mRNA]; nickel chloride promotes the reaction [lipopolysaccharide A results in increased expression of HMOX1 protein]; nickel chloride promotes the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of HMOX1 mRNA] | PMID:16806455 PMID:18830972 PMID:23090859 | |
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