GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Bax | affects expression | EXP | | 6480464 | CTD | nickel chloride affects the expression of BAX mRNA | PMID:22546817 | Bax | increases expression | EXP | | 6480464 | CTD | nickel chloride results in increased expression of BAX protein | PMID:20391133 | Bax | increases expression | ISO | Bax (Mus musculus) | 6480464 | CTD | nickel chloride results in increased expression of BAX mRNA; nickel chloride results in increased expression of BAX protein | PMID:36421005 | Bax | multiple interactions | ISO | Bax (Mus musculus) | 6480464 | CTD | Melatonin inhibits the reaction [nickel chloride results in increased expression of BAX mRNA]; Melatonin inhibits the reaction [nickel chloride results in increased expression of BAX protein]; TXNRD3 gene mutant form inhibits the reaction [Melatonin inhibits the reaction [nickel chloride results in increased expression of BAX mRNA]]; TXNRD3 gene mutant form inhibits the reaction [Melatonin inhibits the reaction [nickel chloride results in increased expression of BAX protein]]; TXNRD3 gene mutant form promotes the reaction [nickel chloride results in increased expression of BAX mRNA]; TXNRD3 gene mutant form promotes the reaction [nickel chloride results in increased expression of BAX protein] | PMID:36421005 | Bax | multiple interactions | ISO | BAX (Homo sapiens) | 6480464 | CTD | [nickel chloride results in increased abundance of Nickel] which results in increased expression of BAX protein; Resveratrol inhibits the reaction [[nickel chloride results in increased abundance of Nickel] which results in increased expression of BAX protein] | PMID:31943712 | |
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