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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1332089
Species: Mus musculus
RGD Object: Gene
Symbol: Aldh1a1
Name: aldehyde dehydrogenase family 1, subfamily A1
Acc ID: CHEBI:34887
Term: nickel dichloride
Definition: A compound of nickel and chloride in which the ratio of nickel (in the +2 oxidation state) to chloride is 1:2.
Chemical ID: MESH:C022838
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Aldh1a1decreases expressionEXP 6480464CTDnickel chloride results in decreased expression of ALDH1A1 mRNAPMID:12729255 PMID:14645679
Aldh1a1increases expressionISOALDH1A1 (Homo sapiens)6480464CTDnickel chloride results in increased expression of ALDH1A1 proteinPMID:26962057
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