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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 734077
Species: Mus musculus
RGD Object: Gene
Symbol: Pold1
Name: polymerase (DNA directed), delta 1, catalytic subunit
Acc ID: CHEBI:34873
Term: N-nitrosodiethylamine
Definition: A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.
Chemical ID: MESH:D004052
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pold1increases expressionEXP 6480464CTDDiethylnitrosamine results in increased expression of POLD1 mRNAPMID:17854601
Pold1multiple interactionsEXP 6480464CTDRB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of POLD1 mRNA]PMID:17854601
Pold1increases expressionISOPold1 (Rattus norvegicus)6480464CTDDiethylnitrosamine results in increased expression of POLD1 mRNAPMID:20360939
Pold1multiple interactionsISOPold1 (Rattus norvegicus)6480464CTDcaffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of POLD1 mRNA]PMID:20360939
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