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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732128
Species: Homo sapiens
RGD Object: Gene
Symbol: RGN
Name: regucalcin
Acc ID: CHEBI:34873
Term: N-nitrosodiethylamine
Definition: A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.
Chemical ID: MESH:D004052
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
RGNdecreases expressionISORgn (Mus musculus)6480464CTDDiethylnitrosamine results in decreased expression of RGN mRNAPMID:24535843
RGNdecreases expressionISORgn (Rattus norvegicus)6480464CTDDiethylnitrosamine results in decreased expression of RGN mRNAPMID:19638242
RGNmultiple interactionsISORgn (Rattus norvegicus)6480464CTD[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in decreased expression of RGN mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased expression of RGN mRNA; [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of RGN mRNA; [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of RGN mRNAPMID:14656948 PMID:16158176 PMID:17602206 PMID:18164116
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