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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730834
Species: Mus musculus
RGD Object: Gene
Symbol: Socs3
Name: suppressor of cytokine signaling 3
Acc ID: CHEBI:34873
Term: N-nitrosodiethylamine
Definition: A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.
Chemical ID: MESH:D004052
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Socs3multiple interactionsISOSocs3 (Rattus norvegicus)6480464CTD[Diethylnitrosamine co-treated with Methylcholanthrene] results in decreased expression of SOCS3 protein; [Diethylnitrosamine co-treated with Methylcholanthrene] results in increased methylation of SOCS3 promoterPMID:20970405
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