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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70971
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hamp
Name: hepcidin antimicrobial peptide
Acc ID: CHEBI:34873
Term: N-nitrosodiethylamine
Definition: A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.
Chemical ID: MESH:D004052
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hampmultiple interactionsEXP 6480464CTD[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of HAMP mRNA; [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of HAMP mRNAPMID:18164116 PMID:20360939
Hampdecreases expressionISOHamp (Mus musculus)6480464CTDDiethylnitrosamine results in decreased expression of HAMP mRNAPMID:19061943
Hampmultiple interactionsISOHamp (Mus musculus)6480464CTDIron inhibits the reaction [Diethylnitrosamine results in decreased expression of HAMP mRNA]PMID:19061943
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