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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69418
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ubd
Name: ubiquitin D
Acc ID: CHEBI:34873
Term: N-nitrosodiethylamine
Definition: A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.
Chemical ID: MESH:D004052
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTD[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of UBD mRNA

PMID:18164116
increases expressionISORGD:694696480464CTDDiethylnitrosamine results in increased expression of UBD mRNA

PMID:18506893
multiple interactionsISORGD:694696480464CTD[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of UBD mRNA, XRCC6 protein inhibits the reaction [Diethylnitrosamine results in increased expression of UBD mRNA]

PMID:18506893, PMID:24535843
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.