GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Pten | decreases expression | EXP | | 6480464 | CTD | Diethylnitrosamine results in decreased expression of PTEN protein | PMID:34726822 | Pten | multiple interactions | EXP | | 6480464 | CTD | maculosin inhibits the reaction [Diethylnitrosamine results in decreased expression of PTEN protein]; Quercetin inhibits the reaction [Diethylnitrosamine results in decreased expression of PTEN protein] | PMID:34726822 | Pten | decreases expression | ISO | Pten (Rattus norvegicus) | 6480464 | CTD | Diethylnitrosamine results in decreased expression of PTEN protein modified form | PMID:19931519 | Pten | multiple interactions | ISO | Pten (Rattus norvegicus) | 6480464 | CTD | 3,4,5,4'-tetramethoxystilbene affects the reaction [[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of PTEN mRNA]; [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of PTEN mRNA; morin inhibits the reaction [Diethylnitrosamine results in decreased expression of PTEN protein modified form] | PMID:19931519 PMID:27048571 | |
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