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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621614
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Plekhb1
Name: pleckstrin homology domain containing B1
Acc ID: CHEBI:34873
Term: N-nitrosodiethylamine
Definition: A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.
Chemical ID: MESH:D004052
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionEXP 6480464CTDDiethylnitrosamine results in decreased expression of PLEKHB1 mRNA

PMID:19638242
multiple interactionsEXP 6480464CTD[Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of PLEKHB1 mRNA

PMID:28943392
decreases expressionISORGD:7336316480464CTDDiethylnitrosamine results in decreased expression of PLEKHB1 mRNA

PMID:24535843
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.