GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nfkbia | increases degradation | EXP | | 6480464 | CTD | Diethylnitrosamine results in increased degradation of NFKBIA protein | PMID:20405173 | Nfkbia | multiple interactions | EXP | | 6480464 | CTD | [Copper co-treated with Diethylnitrosamine co-treated with Iron] results in decreased expression of NFKBIA mRNA; [Copper co-treated with Diethylnitrosamine] results in decreased expression of NFKBIA mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased phosphorylation of NFKBIA protein; [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NFKBIA mRNA; [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of NFKBIA mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of NFKBIA mRNA; [Iron co-treated with Diethylnitrosamine] results in decreased expression of NFKBIA mRNA; Acetylcysteine inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased phosphorylation of NFKBIA protein]; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NFKBIA mRNA]; Resveratrol inhibits the reaction [Diethylnitrosamine results in increased degradation of NFKBIA protein]; S-Adenosylmethionine inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased phosphorylation of NFKBIA protein] | PMID:18404532 PMID:18544905 PMID:20045035 PMID:20302851 PMID:20405173 | Nfkbia | increases expression | ISO | Nfkbia (Mus musculus) | 6480464 | CTD | Diethylnitrosamine results in increased expression of NFKBIA protein | PMID:18691550 PMID:20583210 | Nfkbia | increases phosphorylation | ISO | Nfkbia (Mus musculus) | 6480464 | CTD | Diethylnitrosamine results in increased phosphorylation of NFKBIA protein | PMID:27151938 | Nfkbia | multiple interactions | ISO | Nfkbia (Mus musculus) | 6480464 | CTD | Cholic Acid promotes the reaction [Diethylnitrosamine results in increased phosphorylation of NFKBIA protein]; CTNNB1 protein promotes the reaction [Diethylnitrosamine results in increased expression of NFKBIA protein] | PMID:20583210 PMID:27151938 | | ||||||||||||||||||||||
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