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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2157
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Arrb2
Name: arrestin, beta 2
Acc ID: CHEBI:34873
Term: N-nitrosodiethylamine
Definition: A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.
Chemical ID: MESH:D004052
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Arrb2increases expressionEXP 6480464CTDDiethylnitrosamine results in increased expression of ARRB2 mRNA; Diethylnitrosamine results in increased expression of ARRB2 proteinPMID:21167192 PMID:22393308
Arrb2multiple interactionsEXP 6480464CTDchrysin inhibits the reaction [Diethylnitrosamine results in increased expression of ARRB2 mRNA]; chrysin inhibits the reaction [Diethylnitrosamine results in increased expression of ARRB2 protein]; Plant Oils inhibits the reaction [Diethylnitrosamine results in increased expression of ARRB2 protein]PMID:21167192 PMID:22393308
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