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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2118
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Anxa1
Name: annexin A1
Acc ID: CHEBI:34873
Term: N-nitrosodiethylamine
Definition: A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.
Chemical ID: MESH:D004052
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Anxa1increases expressionEXP 6480464CTDDiethylnitrosamine results in increased expression of ANXA1 mRNA; Diethylnitrosamine results in increased expression of ANXA1 proteinPMID:19638242 PMID:20935162
Anxa1multiple interactionsEXP 6480464CTD[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ANXA1 mRNA; [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of ANXA1 protein; [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of ANXA1 mRNAPMID:18164116 PMID:20935162 PMID:28943392
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