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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1353347
Species: Homo sapiens
RGD Object: Gene
Symbol: EPHB1
Name: EPH receptor B1
Acc ID: CHEBI:34873
Term: N-nitrosodiethylamine
Definition: A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.
Chemical ID: MESH:D004052
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
EPHB1increases phosphorylationISOEphb1 (Mus musculus)127285675RGDN-nitrosodiethylamine increases phosphorylation of Ephb1 protein in liver 
EPHB1multiple interactionsISOEphb1 (Rattus norvegicus)6480464CTD[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of EPHB1 mRNAPMID:22129741
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