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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1311875
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cdc25c
Name: cell division cycle 25C
Acc ID: CHEBI:34873
Term: N-nitrosodiethylamine
Definition: A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.
Chemical ID: MESH:D004052
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cdc25cincreases expressionISOCdc25c (Mus musculus)6480464CTDDiethylnitrosamine results in increased expression of CDC25C mRNAPMID:17854601
Cdc25cmultiple interactionsISOCdc25c (Mus musculus)6480464CTD[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CDC25C protein; RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CDC25C mRNA]PMID:15082532 PMID:17854601
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