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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1311796
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gadd45g
Name: growth arrest and DNA-damage-inducible, gamma
Acc ID: CHEBI:34873
Term: N-nitrosodiethylamine
Definition: A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.
Chemical ID: MESH:D004052
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gadd45gmultiple interactionsEXP 6480464CTD[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of GADD45G mRNAPMID:22129741
Gadd45gincreases expressionISOGadd45g (Mus musculus)6480464CTDDiethylnitrosamine results in increased expression of GADD45G mRNAPMID:17942915
Gadd45gmultiple interactionsISOGadd45g (Mus musculus)6480464CTDMET protein inhibits the reaction [Diethylnitrosamine results in increased expression of GADD45G mRNA]PMID:17942915
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