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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1306605
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp46a1
Name: cytochrome P450, family 46, subfamily a, polypeptide 1
Acc ID: CHEBI:34873
Term: N-nitrosodiethylamine
Definition: A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.
Chemical ID: MESH:D004052
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp46a1decreases expressionISORGD:13153156480464CTDDiethylnitrosamine results in decreased expression of CYP46A1 mRNA

PMID:24535843
Cyp46a1multiple interactionsISORGD:13153156480464CTD[Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of CYP46A1 mRNA

PMID:24535843
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