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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11070
Species: Mus musculus
RGD Object: Gene
Symbol: Pdgfrb
Name: platelet derived growth factor receptor, beta polypeptide
Acc ID: CHEBI:34873
Term: N-nitrosodiethylamine
Definition: A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.
Chemical ID: MESH:D004052
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pdgfrbincreases expressionISOPdgfrb (Rattus norvegicus)6480464CTDDiethylnitrosamine results in increased expression of PDGFRB mRNA; Diethylnitrosamine results in increased expression of PDGFRB proteinPMID:19638242 PMID:26589970
Pdgfrbmultiple interactionsISOPdgfrb (Rattus norvegicus)6480464CTD[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of PDGFRB mRNAPMID:20360939
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