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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1313354
Species: Homo sapiens
RGD Object: Gene
Symbol: NKX3-1
Name: NK3 homeobox 1
Acc ID: CHEBI:34849
Term: mibolerone
Definition: An androgen that is nalandrone carrying two methyl substituents at positions 7alpha and 17.
Chemical ID: MESH:C100075
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NKX3-1increases expressionEXP 6480464CTDmibolerone results in increased expression of NKX3-1 mRNAPMID:10537180
NKX3-1multiple interactionsEXP 6480464CTDFlufenamic Acid inhibits the reaction [mibolerone results in increased expression of NKX3-1 mRNA]; Piroxicam inhibits the reaction [mibolerone results in increased expression of NKX3-1 mRNA]PMID:10537180
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