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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628841
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Trpv1
Name: transient receptor potential cation channel, subfamily V, member 1
Acc ID: CHEBI:34795
Term: 3-isobutyl-1-methyl-7H-xanthine
Definition: A 3-isobutyl-1-methylxanthine that has formula C10H14N4O2.
Chemical ID: MESH:D015056
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Trpv1multiple interactionsEXP 6480464CTD1-Methyl-3-isobutylxanthine promotes the reaction [Capsaicin results in increased activity of TRPV1]PMID:12886029
Trpv1multiple interactionsISOTrpv1 (Mus musculus)6480464CTD[Zeranol co-treated with INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone] results in decreased expression of TRPV1 proteinPMID:33689779
Trpv1multiple interactionsISOTRPV1 (Homo sapiens)6480464CTD1-Methyl-3-isobutylxanthine promotes the reaction [Capsaicin results in increased activity of TRPV1]; [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of TRPV1 mRNAPMID:12886029 PMID:28628672
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