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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621460
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mfn1
Name: mitofusin 1
Acc ID: CHEBI:34787
Term: heptanal
Definition: An n-alkanal resulting from the oxidation of the alcoholic hydroxy group of heptan-1-ol to the corresponding aldehyde. An endogenous aldehyde coming from membrane lipid oxidation, it is found in the blood of lung cancer patients and has been regarded as a potential biomarker of lung cancer.
Chemical ID: MESH:C046204
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mfn1increases methylationISOMFN1 (Homo sapiens)6480464CTDheptanal results in increased methylation of MFN1 genePMID:30002397
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